Health Topics, Conditions and Illnesses > Arrhythmia
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What is Arrhythmia? A Basic Definition
arrhythmia
n : an abnormal rate of muscle contractions
in the heart [syn: cardiac arrhythmia]
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Off-site Arrhythmia Links, User Submitted
The following links have been collected through user bookmark submission in the Arrhythmia category. Please note, because these resources are off-site we cannot guarantee the accuracy or quality of any information.
Fri Jul 4
- A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes -- Luo and Rudy 74 (6): 1071 -- Circulation Research: A mathematical model of the cardiac ventricular action potential is presented. The model presented here for the mammalian ventricular action potential is based mostly on the guinea pig ventricular cell.
- Effects of IKr and IKs Heterogeneity on Action Potential Duration and Its Rate Dependence : A Simulation Study -- Viswanathan et al. 99 (18): 2466 -- Circulation: Heterogeneity of IKs:IKr density strongly influences APD and its rate dependence. However, in the intact myocardium, the degree of gap-junction coupling may be an important factor that determines the manifestation of APD heterogeneity and dispersion of re
- Action Potential and Contractility Changes in [Na+]i Overloaded Cardiac Myocytes: A Simulation Study -- Faber and Rudy 78 (5): 2392 -- Biophysical Journal: We investigate effects of elevated intracellular sodium on the cardiac action potential (AP) and on intracellular calcium using the Luo-Rudy model of a mammalian ventricular myocyte.
Thu Jul 3
Wed Jun 25
- Ca(V)1.2 calcium channel dysfunction causes a mult...[Cell. 2004] - PubMed Result: Functional expression reveals that G406R produces maintained inward Ca(2+) currents by causing nearly complete loss of voltage-depend ent channel inactivation. This likely induces intracellular Ca(2+) overload in multiple cell types.
Tue Jun 24
- CaM kinase augments cardiac L-type Ca2+ current: a cellular mechanism for long Q-T arrhythmias -- Wu et al. 276 (6): H2168 -- AJP - Heart and Circulatory Physiology: Ultrastructura l studies confirmed that endogenous CaM kinase, L-type Ca2+ channels, and ryanodine receptors colocalized near T tubules. These findings support the hypothesis that EADs are facilitated by CaM kinase.
- Effects of Na+/Ca2+ exchange induced by SR Ca2+ release on action potentials and afterdepolariz ations in guinea pig ventricular myocytes -- Spencer and Sham 285 (6): H2552 -- AJP - Heart and Circulatory Physiology: Na+/Ca2+ exchange is a major physiological determinant of APD and that INaCa activation by spontaneous SR Ca2+ release/oscill ations, depending on the timing, can account for both DADs and EADs during SR Ca2+ overload.
Tue Jun 10
- St. David's HealthCare - St. David's HealthCare and Texas Cardiac Arrhythmia Announce International Center for Training, Research and Treatment of Heart Rhythm Disorders
- Texas Cardiovascular Consultants - Physicians
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